Our newborn interesting paper: Primary intraosseous Papillary Intralymphatic  Angioendothelioma (PILA) distal femur.

PILAs of bone are exceedingly rare tumors.

We present a case of PILA arising in the distal femoral epiphysis of a 50-year-old female patient. Primary intraosseous PILAs are exceedingly rare tumors that should be considered in the differential diagnosis of vascular bone tumors.

Organization (WHO) tumor classification, they are considered an intermediate (rarely metastasizing) neoplasm (Julie C. Fanburg-Smith, M.D. Papillary intralymphatic angioendothelioma. In: WHO classification of tumours of soft tissue and bone. 5th. Agency for Research on Cancer; 2020:161–162) The majority are located in subcutaneous tissue,although a few cases have arisen in deeper locations such as the tongue, spleen, testi, or atrium. Only four cases have been reported in bone.